I make a trip to South Dakota once a year with my brother-in-law & father-in-law to shoot prairie dogs. I take a 223, 44mag henry lever action, 22 pistol, 17 hmr & 45 colt Ruger. The in-laws shoot primarily 22-250.
We each go through 500-1000 rounds depending on if we get good weather. We ran into rain/wind the last couple of years so we didn't shoot as much. It's still a good time though. We typically just drive around in a truck and stop to setup for shooting. I'm planning on taking the buggy with me this year and they are going to take their ATVs.
Here's a couple video links of our 2009 & 2010 trips
http://www.youtube.com/watch?v=1ZB2fynHvSo
http://www.youtube.com/watch?v=pnIWbzYfNVM&feature=fvsr